Tetraspanin 4 (TSPAN4)
NAG-2; NAG2; TETRASPAN; TM4SF7; TSPAN-4; transmembrane 4 superfamily member 7; Novel antigen 2
Tetraspanin-4 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.Expressed in multiple tissues but is absent in brain, lymphoid cells, and platelets.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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