Trace Amine Associated Receptor 4 (TAAR4)
Gm226; TaR-4; 2-phenylethylamine receptor
The family of trace amine-associated receptors (TAAR) comprises 9 mammalian TAAR subtypes, with intact gene and pseudogene numbers differing considerably even between closely related species. To date the best characterized subtype is TAAR1, which activates the G(s) protein/adenylyl cyclase pathway upon stimulation by trace amines and psychoactive substances like MDMA or LSD. Recently, chemosensory function involving recognition of volatile amines was proposed for murine TAAR3, TAAR4 and TAAR5. Humans can smell volatile amines despite carrying open reading frame (ORF) disruptions in TAAR3 and TAAR4. Functional analyses showed that ligands activating the murine TAAR3, TAAR4 and TAAR5 do not activate intact primate and mammalian orthologs, although they evolve under purifying selection and hence must be functional.
Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Trace Amine Associated Receptor 4 (TAAR4) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Trace Amine Associated Receptor 4 (TAAR4) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Trace Amine Associated Receptor 4 (TAAR4) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Trace Amine Associated Receptor 4 (TAAR4) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Trace Amine Associated Receptor 4 (TAAR4) ELISA Kit Customized Service Offer