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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Transcription Factor 7 Like Protein 2 (TCF7L2)
TCF4
TCF7L2 encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes.TCF7L1 and TCF7L2 were not expressed in cells of the lymphoid lineage. The deduced amino acid sequences of the HMG boxes of TCF7L1, TCF7L2, and TCF7 show striking homology. That gene activation by the beta-catenin/TCF4 complex is a critical event in cancer development is indicated by the fact that a subset of colorectal cancers that lack somatic mutations in APC show somatic mutations in the beta-catenin gene. These mutations are presumed to render beta-catenin insensitive to regulation by APC and GSK3B.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPP601Hu01 Recombinant Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
Antibodies PAP601Hu01 Polyclonal Antibody to Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
MAP601Hu21 Monoclonal Antibody to Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
Assay Kits SEP601Hu ELISA Kit for Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
SCP601Hu CLIA Kit for Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPP601Mu01 Recombinant Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
Antibodies PAP601Mu01 Polyclonal Antibody to Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
MAP601Mu21 Monoclonal Antibody to Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
Assay Kits SEP601Mu ELISA Kit for Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
SCP601Mu CLIA Kit for Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPP601Ra01 Recombinant Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
Antibodies PAP601Ra01 Polyclonal Antibody to Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
MAP601Ra21 Monoclonal Antibody to Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
Assay Kits SEP601Ra ELISA Kit for Transcription Factor 7 Like Protein 2 (TCF7L2) Customize
SCP601Ra CLIA Kit for Transcription Factor 7 Like Protein 2 (TCF7L2) Customize