Tuftelin Interacting Protein 11 (TFIP11)
TIP39; STIP-1; Septin and tuftelin-interacting protein 1
TFIP11 is a nuclear speckle-localized protein that may play a role in spliceosome disassembly in Cajal bodies ,which encodes a deduced 837-amino acid protein with a calculated molecular mass of 96.8 kD. The deduced 678-amino acid mouse protein shares 92% amino acid identity with human TFIP11. Both human and mouse proteins contain a myc-type HLH domain, at least 2 coiled-coil domains, and a C-terminal clathrin-binding motif. In situ hybridization of 1-day-old mouse mandible detected Tfip11 transcripts in secretory ameloblasts and odontoblasts. In vitro and in vivo analysis showed that Tfip11 and Tuft1 colocalized.Tfip11 colocalized with splicing factor SC35 (SFRS2), a marker for nuclear speckles, and was distinct and excluded from paraspeckles.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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- Customized Service n/a Monoclonal Antibody to Tuftelin Interacting Protein 11 (TFIP11) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Tuftelin Interacting Protein 11 (TFIP11) Polyclonal Antibody Customized Service Offer
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- Customized Service n/a ELISA Kit for Tuftelin Interacting Protein 11 (TFIP11) ELISA Kit Customized Service Offer