U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2)
U2AF65; •U2 auxiliary factor 65 kDa subunit; U2 snRNP auxiliary factor large subunit; Splicing factor U2AF 65 kDa subunit
U2 auxiliary factor (U2AF), composed of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 encodes the U2AF large subunit, which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple alternatively spliced transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.U2AF65 splicing factor undergoes posttranslational lysyl-5-hydroxylation catalyzed by the Fe(II)- and 2-oxoglutarate-dependent dioxygenase Jumonji domain-6 protein (JMJD6).
Organism species: Homo sapiens (Human)
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- Customized Service n/a Monoclonal Antibody to U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2) Polyclonal Antibody Customized Service Offer
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- Customized Service n/a ELISA Kit for U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2) ELISA Kit Customized Service Offer