Ubiquitin Conjugating Enzyme E2T (UBE2T)
HSPC150; Cell proliferation-inducing gene 50 protein; Ubiquitin carrier protein T; Ubiquitin-protein ligase T
The covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3). This monoubiquitination was stimulated by the presence of FANCL and inactivated UBE2T. UBE2T activity was dependent on the conserved cys86, where a ubiquitin molecule is transferred from E1, and UBE2T underwent automonoubiquitination at lys91 in vivo. The monoubiquitination of UBE2T occurred even in the absence of an E3 in vitro.The deduced 197-amino acid protein contains a ubiquitin-conjugating enzyme active site. EST database analysis indicated widespread UBE2T expression.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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- Customized Service n/a Monoclonal Antibody to Ubiquitin Conjugating Enzyme E2T (UBE2T) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Ubiquitin Conjugating Enzyme E2T (UBE2T) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Ubiquitin Conjugating Enzyme E2T (UBE2T) CLIA Kit Customized Service Offer
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Organism species: Rattus norvegicus (Rat)
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- Customized Service n/a Monoclonal Antibody to Ubiquitin Conjugating Enzyme E2T (UBE2T) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Ubiquitin Conjugating Enzyme E2T (UBE2T) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Ubiquitin Conjugating Enzyme E2T (UBE2T) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Ubiquitin Conjugating Enzyme E2T (UBE2T) ELISA Kit Customized Service Offer