Ubiquitination Factor E4B (UBE4B)
UBOX3; E4; UFD2; HDNB1; Homozygously deleted in neuroblastoma 1; Ubiquitin fusion degradation protein 2
UBE4Bencodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
UBE4B has a C-terminal U-box domain including a proline residue perfectly conserved among U-box proteins. The deduced 903-amino acid protein shares weak similarity with Dictyostelium NOSA, a developmental regulator involved in proteasomal degradation of ubiquitinated proteins. Ufd2a interacted with Vcp, a AAA-family ATPase implicated in protein folding. the mouse Ube4b gene contains 27 coding exons.
Organism species: Homo sapiens (Human)
- Customized Service n/a Recombinant Ubiquitination Factor E4B (UBE4B) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Ubiquitination Factor E4B (UBE4B) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Ubiquitination Factor E4B (UBE4B) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Ubiquitination Factor E4B (UBE4B) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Ubiquitination Factor E4B (UBE4B) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Ubiquitination Factor E4B (UBE4B) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Ubiquitination Factor E4B (UBE4B) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Ubiquitination Factor E4B (UBE4B) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Ubiquitination Factor E4B (UBE4B) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Ubiquitination Factor E4B (UBE4B) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Ubiquitination Factor E4B (UBE4B) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Ubiquitination Factor E4B (UBE4B) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Ubiquitination Factor E4B (UBE4B) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Ubiquitination Factor E4B (UBE4B) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Ubiquitination Factor E4B (UBE4B) ELISA Kit Customized Service Offer