V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)

C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS3; RASK2
V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)
Like other members of the Ras family, the KRAS protein is a GTPase and is an early player in many signal transduction pathways. KRAS is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. When mutated, KRAS is a oncogene. The protein product of the normal KRAS gene performs an essential function in normal tissue signaling, and the mutation of a KRAS gene is an essential step in the development of many cancers.KRAS acts as a molecular on/off switch, once it is turned on it recruits and activates proteins necessary for the propagation of growth factor and other receptors' signal, such as c-Raf and PI 3-kinase. KRAS binds to GTP in the active state and possesses an intrinsic enzymatic activity which cleaves the terminal phosphate of the nucleotide converting it to GDP.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
  • Protein RPH751Mu01Recombinant V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)Customize
  • AntibodyPAH751Mu01Polyclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)Customize
  • AntibodyMAH751Mu21Monoclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)Customize
  • Assay KitSEH751MuELISA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)Customize
  • Assay KitSCH751MuCLIA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPH751Ra01Recombinant V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)Customize
  • AntibodyPAH751Ra01Polyclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)Customize
  • AntibodyMAH751Ra21Monoclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)Customize
  • Assay KitSEH751RaELISA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)Customize
  • Assay KitSCH751RaCLIA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)Customize
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