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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)
C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS3; RASK2
Like other members of the Ras family, the KRAS protein is a GTPase and is an early player in many signal transduction pathways. KRAS is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. When mutated, KRAS is a oncogene. The protein product of the normal KRAS gene performs an essential function in normal tissue signaling, and the mutation of a KRAS gene is an essential step in the development of many cancers.KRAS acts as a molecular on/off switch, once it is turned on it recruits and activates proteins necessary for the propagation of growth factor and other receptors' signal, such as c-Raf and PI 3-kinase. KRAS binds to GTP in the active state and possesses an intrinsic enzymatic activity which cleaves the terminal phosphate of the nucleotide converting it to GDP.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPH751Hu01 Recombinant V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
Antibodies MAH751Hu21 Monoclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
PAH751Hu01 Polyclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
Assay Kits SEH751Hu ELISA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) In Stock
SCH751Hu CLIA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPH751Mu01 Recombinant V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
Antibodies PAH751Mu01 Polyclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
MAH751Mu21 Monoclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
Assay Kits SEH751Mu ELISA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
SCH751Mu CLIA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPH751Ra01 Recombinant V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
Antibodies PAH751Ra01 Polyclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
MAH751Ra21 Monoclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
Assay Kits SEH751Ra ELISA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize
SCH751Ra CLIA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Customize