Valosin Containing Protein p97/p47 Complex Interacting Protein 1 (VCPIP1)
VCIP135; Valosin-containing protein p97/p47 complex-interacting protein p135
The deduced protein contains 1,236 amino acids. RT-PCR ELISA detected moderate VCPIP1 expression in all adult and fetal tissues examined.Reassembly of the Golgi apparatus from membrane fragments after cell division requires the ATPases NSF and p97 (VCP), as well as the cofactor p47 (NSFL1C) and the receptor syntaxin-5 (STX5A). rat Vcip135 was essential for p97/p47-mediated membrane fusion and that Vcip135 bound to the p97/p47/Stx5a complex and dissociated it via p97-catalyzed ATP hydrolysis. Microinjection of antibodies against Vcip135 and p47 in rat kidney cells showed that Vcip135 and p47 were required for Golgi and endoplasmic reticulum assembly.a cycle of ubiquitination and VCIP135-mediated deubiquitination regulates Golgi membrane dynamics during mitosis.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Valosin Containing Protein p97/p47 Complex Interacting Protein 1 (VCPIP1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Valosin Containing Protein p97/p47 Complex Interacting Protein 1 (VCPIP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Valosin Containing Protein p97/p47 Complex Interacting Protein 1 (VCPIP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Valosin Containing Protein p97/p47 Complex Interacting Protein 1 (VCPIP1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Valosin Containing Protein p97/p47 Complex Interacting Protein 1 (VCPIP1) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Valosin Containing Protein p97/p47 Complex Interacting Protein 1 (VCPIP1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Valosin Containing Protein p97/p47 Complex Interacting Protein 1 (VCPIP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Valosin Containing Protein p97/p47 Complex Interacting Protein 1 (VCPIP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Valosin Containing Protein p97/p47 Complex Interacting Protein 1 (VCPIP1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Valosin Containing Protein p97/p47 Complex Interacting Protein 1 (VCPIP1) ELISA Kit Customized Service Offer