Vesicle Associated Membrane Protein 5 (VAMP5)

VAMPs (synaptobrevins) along with syntaxins and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes.

The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis.deduced 102-amino acid protein is predicted to contain a cytoplasmic coiled-coil structure at the N terminus, a hydrophobic domain, and a short hydrophilic C-terminal sequence. Vamp5 shares 33% sequence identity with cellubrevin (VAMP3) and synaptobrevin/Vamp2.