Werner syndrome, RecQ Helicase Like (WRN)

RECQL2; RECQL3; RECQ3; Werner syndrome ATP-dependent helicase; DNA helicase, RecQ-like type 3; Exonuclease WRN; RecQ protein-like 2

Werner syndrome, RecQ Helicase Like (WRN)
WRN (Werner syndrome) is a human gene that provides instructions for producing Werner protein, which is a type of enzyme called a helicase. Helicase enzymes generally unwind and separate double-stranded DNA. These activities are necessary before DNA can be copied in preparation for cell division (DNA replication). Helicase enzymes are also critical for making a blueprint of a gene for protein production, a process called transcription. Further evidence suggests that Werner protein plays a critical role in repairing DNA. Overall, this protein helps maintain the structure and integrity of a person's DNA. The WRN gene is located on the short (p) arm of chromosome 8 between positions 12 and 11.2, from base pair 31,010,319 to base pair 31,150,818.

Organism species: Homo sapiens (Human)

Organism species: Mus musculus (Mouse)