X-Kell Blood Group Precursor Related Family, Member 5 (XKR5)
XRG5; XK-related protein 5
XKR5 belongs to the XK family. XK is a protein found on human red blood cells and other tissues which is responsible for the Kx antigen which helps determine a person's blood type. The Kx antigen plays a role in matching blood for blood transfusions. Absence of XK protein leads to McLeod syndrome, a multi-system disorder characterized by hemolytic anemia, myopathy, acanthocytosis, and chorea.
XK is located on the X chromosome and absence of the XK protein is an X-linked disease. XK is a membrane transport protein of unknown action.The XK locus is inactivated by lyonization. The precursor missing in McLeod's red cells is called Kx. The X-linked locus determining this substance is called XK.
XK is located on the X chromosome and absence of the XK protein is an X-linked disease. XK is a membrane transport protein of unknown action.The XK locus is inactivated by lyonization. The precursor missing in McLeod's red cells is called Kx. The X-linked locus determining this substance is called XK.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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