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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Xeroderma Pigmentosum, Complementation Group A (XPA)
XP-A; XPAC; XP1
XPA encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. The deduced 273-amino acid protein has a calculated molecular mass of 31 kD. The human protein is 95% similar to the mouse protein and contains several alpha-helices and a zinc-finger motif, consistent with a DNA-binding protein. Two mRNAs, 1.3-1.4 kb and 1.0-1.1 kb, were detected in normal human cells. Sequence analysis identified a truncated XPA protein that could be translated from an ATG present at position 176, which retained sufficient function to partially restore the DNA repair defect in XPA cells. A 1.0-1.1-kb mouse Xpa mRNA was also identified.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPE744Hu01 Recombinant Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
Antibodies PAE744Hu01 Polyclonal Antibody to Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
MAE744Hu21 Monoclonal Antibody to Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
Assay Kits SEE744Hu ELISA Kit for Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
SCE744Hu CLIA Kit for Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPE744Mu01 Recombinant Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
Antibodies PAE744Mu01 Polyclonal Antibody to Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
MAE744Mu21 Monoclonal Antibody to Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
Assay Kits SEE744Mu ELISA Kit for Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
SCE744Mu CLIA Kit for Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPE744Ra01 Recombinant Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
Antibodies PAE744Ra01 Polyclonal Antibody to Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
MAE744Ra21 Monoclonal Antibody to Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
Assay Kits SEE744Ra ELISA Kit for Xeroderma Pigmentosum, Complementation Group A (XPA) Customize
SCE744Ra CLIA Kit for Xeroderma Pigmentosum, Complementation Group A (XPA) Customize