YTH Domain Family, Member 1 (YTHDF1)
C20orf21; DACA-1; Dermatomyositis Associated With Cancer Putative Autoantigen 1
YTHDF1, Contains 1 YTH domain. The YTH (YT521-B homology) domain was identified by sequence comparison and is found in 174 different proteins expressed in eukaryotes. It is characterized by 14 invariant residues within an alpha-helix/beta-sheet structure. YTH domain is a novel RNA binding domain that binds to a short, degenerated, single-stranded RNA sequence motif. The presence of the binding motif in alternative exons is necessary for YT521-B to directly influence splice site selection in vivo. Array analyses demonstrate that YT521-B predominantly regulates vertebrate-specific exons. An NMR titration experiment identified the binding surface for single-stranded RNA on the YTH domain. Structural analyses indicate that the YTH domain is related to the pseudouridine synthase and archaeosine transglycosylase (PUA) domain.
Organism species: Homo sapiens (Human)
- Customized Service n/a Recombinant YTH Domain Family, Member 1 (YTHDF1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to YTH Domain Family, Member 1 (YTHDF1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to YTH Domain Family, Member 1 (YTHDF1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for YTH Domain Family, Member 1 (YTHDF1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for YTH Domain Family, Member 1 (YTHDF1) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant YTH Domain Family, Member 1 (YTHDF1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to YTH Domain Family, Member 1 (YTHDF1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to YTH Domain Family, Member 1 (YTHDF1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for YTH Domain Family, Member 1 (YTHDF1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for YTH Domain Family, Member 1 (YTHDF1) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant YTH Domain Family, Member 1 (YTHDF1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to YTH Domain Family, Member 1 (YTHDF1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to YTH Domain Family, Member 1 (YTHDF1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for YTH Domain Family, Member 1 (YTHDF1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for YTH Domain Family, Member 1 (YTHDF1) ELISA Kit Customized Service Offer