Zinc Finger, DHHC-Type Containing Protein 11B (ZDHHC11B)

Zinc Finger, DHHC-Type Containing Protein 11B (ZDHHC11B)
ZDHHC11B Belongs to the DHHC palmitoyltransferase family.Contains 1 DHHC-type zinc finger.The DHHC domain is required for palmitoyltransferase activity. In molecular biology the DHHC domain is a protein domain that acts as an enzyme, which adds a palmitoyl chemical group to proteins in order to anchor them to cell membranes. The DHHC domain was discovered in 1999 and named after a conserved sequence motif found in its protein sequence. Roth and colleagues showed that the yeast Akr1p protein could palmitoylate Yck2p in vitro and inferred that the DHHC domain defined a large family of palmitoyltransferases. In mammals twenty three members of this family have been identified and their substrate specificities investigated.Several members of the family have been implicated in human diseases.

Organism species: Homo sapiens (Human)