Zinc Finger, DHHC-Type Containing Protein 2 (ZDHHC2)

Zinc fingers are small protein structural motifs that can coordinate one or more zinc ions to help stabilize their folds. They can be classified into several different structural families and typically function as interaction modules that bind DNA, RNA, proteins, or small molecules.

Zdhhc2, a new target involved in adipogenesis modulation. decrease in Zdhhc2 activity in adipose tissue induces a decrease in adipogenesis. modulators of Zdhhc2 activity as well as screening test for identification of modulators of the activity of this target, and their use, especially in pharmaceutical composition, to modulate adipogenesis and thus treat obesity and related disorders.