Zinc Finger Protein 654 (ZNF654)

The ZNF654 gene, located on chromosome 17, encodes a protein that is part of the zinc finger family. Belongs to the krueppel C2H2-type zinc-finger protein family.The Cys₂His₂-like fold group is by far the best-characterized class of zinc fingers and are extremely common in mammalian transcription factors.

Zinc fingers are small protein structural motifs that can coordinate one or more zinc ions to help stabilize their folds. They can be classified into several different structural families and typically function as interaction modules that bind DNA, RNA, proteins, or small molecules. The name "zinc finger" was originally coined to describe the hypothesized structure of the repeated unit in Xenopus laevis transcription factor IIIA.