Zona Pellucida Glycoprotein 2, Sperm Receptor (ZP2)
ZPA; Zona Pellucida Sperm-Binding Protein 2 ; Zona pellucida protein A
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. Zona pellucida sperm-binding protein 2 is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Zona Pellucida Glycoprotein 2, Sperm Receptor (ZP2) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Zona Pellucida Glycoprotein 2, Sperm Receptor (ZP2) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Zona Pellucida Glycoprotein 2, Sperm Receptor (ZP2) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Zona Pellucida Glycoprotein 2, Sperm Receptor (ZP2) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Zona Pellucida Glycoprotein 2, Sperm Receptor (ZP2) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPC612Ra01 Recombinant Zona Pellucida Glycoprotein 2, Sperm Receptor (ZP2) In Stock
- Polyclonal antibody PAC612Ra01 Polyclonal Antibody to Zona Pellucida Glycoprotein 2, Sperm Receptor (ZP2) In Stock
- Monoclonal antibody MAC612Ra21 Monoclonal Antibody to Zona Pellucida Glycoprotein 2, Sperm Receptor (ZP2) In Stock
- Sandwich ELISA SEC612Ra ELISA Kit for Zona Pellucida Glycoprotein 2, Sperm Receptor (ZP2) In Stock