Active Interleukin 34 (IL34) Mus musculus (Mouse) Active protein

C16orf77

Add to Cart Distributors
Overview
Properties
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point7.7
Share your citation Upload your experimental result Review Leave a message
Loading...

Share a new citation as an author

Upload your experimental result

Review

Please attach serial No. on instruction manual

Contact us

Please fill in the blank.

Name*
Organization
Address
E-mail address*
Telephone
Inquiry*
Verification code* CheckCode
  • Active Interleukin 34 (IL34) Packages (Simulation)
  • Active Interleukin 34 (IL34) Packages (Simulation)
  • APC007Mu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Activity test

Interleukin 34 (IL-34) is a protein belonging to a group of cytokines called interleukins. IL-34 increases growth or survival of immune cells known as monocytes; it elicits its activity by binding the Colony stimulating factor 1 receptor. To explore the effect of IL-34 induction of bone marrow cells differentiation into macrophages,1×106 density of bone marrow cells were cultured with different concentration of recombinant mouse IL-34 for 7days, every three day changed with fresh culture. Setting the blank well without IL-34 as the control well. After 7days later, bone marrow cells culture with 1ug/ml IL-34 were significantiy differentiation into macrophages. The result observed by inverted microscope was shown on Figure1. Ink phagocytosis test shows ,after stimulated by IL-34, most of cells have phagocytosis function. The results were shown on Figure2.

Figure2. Ink phagocytosis test.

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Increased Serum Interleukin-34 in Patients with Coronary Artery DiseasePubMed: 23206468
  • IL-34 inhibits acute rejection of rat liver transplantation by inducing Kupffer cell M2 polarizationPubmed:29570162
  • КЛИНИКО-ЭПИДЕМИОЛОГИЧЕСКАЯ ХАРАКТЕРИСТИКА И ОСОБЕННОСТИ БАЛЛАНСА ЦИТОКИНОВ ПРИ КЛЕЩЕВОМ ЭНЦЕФАЛИТЕ В …
  • A comparison of IL-17 and IL-34 concentrations in the cerebrospinal fluid of patients with acute inflammatory demyelinating neuropathy and chronic …
  • A comparison of IL-17 and IL-34 concentrations in the cerebrospinal fluid of patients with acute inflammatory demyelinating neuropathy and chronic?¡­33295414

Recommend products