Recombinant Angiotensin I Converting Enzyme (ACE)Homo sapiens (Human)Recombinant protein

CD143; ACE1; DCP1; ACEI; ACE-I; Kininase II; Angiotensin-Converting Enzyme; Peptidyl-Dipeptidase A; Dipeptidyl Carboxypeptidase 1; Angiotensin-converting enzyme, soluble form

  • Product No.RPA004Hu01
  • Organism SpeciesHomo sapiens (Human)Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular Locationn/a
  • Predicted Molecular Mass61.5kDa
  • Accurate Molecular Massn/a(Analysis of differences refer to the manual)
  • Residues & TagsArg814~Gln1071 (Accession # P12821) with N-terminal His and GST Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • TraitsFreeze-dried powder
  • Purity> 95%
  • Isoelectric Pointn/a
  • ApplicationsSDS-PAGE; WB; ELISA; IP.
  • DownloadInstruction Manual
  • UOM10ug50ug200ug1mg1g
  • FOBUS$ 154US$ 384US$ 768US$ 2304US$ 57600
  • Recombinant Angiotensin I Converting Enzyme (ACE)Package and Components
  • Recombinant Angiotensin I Converting Enzyme (ACE)Package and Components
    • RPA004Hu01.jpgSDS-PAGE
    • CertificateISO9001: 2008, ISO13485: 2003 Registered

    SEQUENCE

    USAGE

    Reconstitute in PBS or others.

    STORAGE

    Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

    STABILITY

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

    Reference

    • Lipids in Health and diseaseAssociation of elevated blood pressure and impaired vasorelaxation in experimental Sprague-Dawley rats fed with heated vegetable oilPubMed: PMC2914008
    • Malaysian Journal of Medical SciencesEffect of Repeatedly Heated Palm Olein on Blood Pressureā€“Regulating Enzymes Activity and Lipid Peroxidation in RatsUsm: MJMS19120
    • Journal of Cancer TherapyPlasma Levels of Angiotensin-Converting Enzymes 1 and 2 and AGTR2 (T1247G and A5235G) Gene Polymorphisms Are Associated to Breast Cancer Progression.Scirp: Source
    • The American journal of clinical nutritionVascular function and atherosclerosis progression after 1 y of flavonoid intake in statin-treated postmenopausal women with type 2 diabetes: a double-blind randomized controlled trial.Pubmed: 23553151
    • Journal of Vascular SurgeryCathepsin G deficiency reduces periaortic calcium chloride injury-induced abdominal aortic aneurysms in mice Pubmed:25037606
    • Reprod Toxicol.?ACE2 activation by xanthenone prevents leptin-induced increases in blood pressure and proteinuria during pregnancy in Sprague-Dawley ratsPubmed:25205467
    • Chemical Research in ToxicologySub-chronic Toxicity and Cardiovascular Responses in Spontaneously Hypertensive Rats after Exposure to Multiwall Carbon Nanotubes by Intratracheal InstillationPubmed:25580880
    • Chem Biol InteractArsenic causes aortic dysfunction and systemic hypertension in rats: Augmentation of angiotensin II signalingPubMed: 26079204
    • Biomed Res IntProtective Effect of Enalapril against Methionine-Enriched Diet-Induced Hypertension: Role of Endoplasmic Reticulum and Oxidative StressPubMed: 26640794
    • Clinics (Sao Paulo)MechanismsPubMed: 26602523
    • Chemical Research in ToxicologySubchronic Toxicity and Cardiovascular Responses in Spontaneously Hypertensive Rats after Exposure to Multiwalled Carbon Nanotubes by Intratracheal InstillationPubMed: 25580880
    • Intensive Care Medicine Experimental Angiotensin converting enzymes in patients with acute respiratory distress syndromeContent: 3
    • Evid Based Complement Alternat Med.Garlic Attenuates Plasma and Kidney ACE-1 and AngII Modulations in Early Streptozotocin-Induced Diabetic Rats: Renal Clearance and Blood Pressure ImplicationsPubmed:27293465