Recombinant Glutathione Peroxidase 3, Plasma (GPX3) Homo sapiens (Human) Recombinant protein

GSHPX3; GPx-P; GSHPx-P; GPXP; Plasma glutathione peroxidase; Extracellular glutathione peroxidase

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 9.5kDa, Accurate 10kDa(Analysis of differences refer to the manual)
  • Residues & TagsGln21~Tyr72 with N-terminal His Tag
  • Buffer Formulation100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point7.1
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  • Recombinant Glutathione Peroxidase 3, Plasma (GPX3) Packages (Simulation)
  • Recombinant Glutathione Peroxidase 3, Plasma (GPX3) Packages (Simulation)
  • Recombinant Glutathione Peroxidase 3, Plasma (GPX3) Figure. Gene Sequencing (Extract)
  • RPC992Hu01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Alteration in the intrafollicular thiol–redox system in infertile women with endometriosisPubmed:25376627
  • Endothelial function impairment in STEMI patients with out-of-hospital cardiac arrest under therapeutic hypothermia treatment.pubmed:28087172
  • Comparison of Extracellular and Intracellular Blood Compartments Highlights Redox Alterations in Alzheimer's and Mild Cognitive Impairment Patients.pubmed:27748187
  • Burn Serum Increases Staphylococcus aureus Biofilm Formation via Oxidative Stress.pubmed:28702016
  • Hydrogen peroxide-induced mitophagy contributes to laryngeal cancer cells survival via the upregulation of FUNDC1Pubmed: 30284230
  • Kidney toxicity and response of selenium containing protein-glutathione peroxidase (Gpx3) to CdTe QDs on different levelsPubmed: 30535317
  • Human Plasma Protein (s) Based Conceptual Diagnostic Tool for Altitude-Acclimation Assessment
  • Dietary selenium deficiency or selenomethionine excess drastically alters organ selenium contents without altering the expression of most selenoproteins in mice
  • Molecular mechanisms of lead-induced changes of selenium status in mice livers through interacting with selenoprotein P
  • In vivo and in vitro studies on inactivation of selenium containing protein-glutathione peroxidase 3 in mice nephrocytes caused by leadPubmed: 32678766
  • Selenium–GPX4 axis protects follicular helper T cells from ferroptosis34413521
  • Experimental nephrotic syndrome in mice with an inducible deletion of podocin and the role of plasminogen in sodium retention

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