Recombinant Heparan Sulfate Proteoglycan 2 (HSPG2) Mus musculus (Mouse) Recombinant protein

PLC; PRCAN; SJA; SJS; SJS1; Perlecan; Endorepellin; Schwartz-Jampel Syndrome 1; Basement membrane-specific heparan sulfate proteoglycan core protein

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Secreted, Extracellular matrix
  • Molecular Mass 35.3kDa, Accurate 40kDa(Analysis of differences refer to the manual)
  • Residues & TagsGlu4012~Glu4304 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point4.7
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  • Recombinant Heparan Sulfate Proteoglycan 2 (HSPG2) Packages (Simulation)
  • Recombinant Heparan Sulfate Proteoglycan 2 (HSPG2) Packages (Simulation)
  • Recombinant Heparan Sulfate Proteoglycan 2 (HSPG2) Figure . Gene Sequencing (extract)
  • RPC748Mu01.png Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Suramin inhibits hepatic tissue damage in hepatocellular carcinoma through deactivation of heparanase enzymePubmed: 24530413
  • Proteomics of Follicular Fluid From Women With Polycystic Ovary Syndrome Suggests Molecular Defects in Follicular DevelopmentPubmed:25393639
  • Key Matrix Proteins Within the Pancreatic Islet Basement Membrane Are Differentially Digested During Human Islet Isolation.pubmed:27456745
  • Expression and Circulating Levels of Perlecan in Breast Cancer-Implications for Oestrogen Dependent Stromal RemodelingPubmed: 32124140

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