Recombinant Mannose Associated Serine Protease 1 (MASP1) Homo sapiens (Human) Recombinant protein

CRARF; PRSS5; Mannan-Binding Lectin Serine Peptidase 1; Ra-reactive factor serine protease p100; Complement-activating component of Ra-reactive factor; Serine protease 5

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 52.7kDa, Accurate 53kDa(Analysis of differences refer to the manual)
  • Residues & TagsHis20~Ala447 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point5.2
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  • Recombinant Mannose Associated Serine Protease 1 (MASP1) Packages (Simulation)
  • Recombinant Mannose Associated Serine Protease 1 (MASP1) Packages (Simulation)
  • Recombinant Mannose Associated Serine Protease 1 (MASP1) Figure . Gene Sequencing (extract)
  • RPB895Hu01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Increased Circulating Plasma Mannose Binding Lectin Associated Serine Protease (Masp) As A Result of Enu-Induced Mutation in Masp-1Lww: Source
  • Bisretinoid-mediated Complement Activation on Retinal Pigment Epithelial Cells Is Dependent on Complement Factor H HaplotypePubmed:24550392
  • The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary AngioedemaPubMed: 26371246
  • Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitisPMC5234106
  • AmpliSeq screening of genes encoding the C-type lectin receptors and their signaling components reveals a common variant in MASP1 associated with …Pubmed:29515573
  • Plasma proteome profiling of high-altitude polycythemia using TMT-based quantitative proteomics approachPubmed: 30605725
  • Clinical value of complement activation biomarkers in overt diabetic nephropathy
  • Comparison of Complement Pathway Activation in Autoimmune GlomerulonephritisPubmed:35571000

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