Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) Rattus norvegicus (Rat) Recombinant protein

MOX1; GP91-2; NOH1; NADPH Oxidase 1; Mitogenic Oxidase(Pyridine Nucleotide-Dependent Superoxide-Generating; NADH/NADPH mitogenic oxidase subunit P65-MOX

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Molecular Mass 32.8KDa, Accurate 32.8kDa(Analysis of differences refer to the manual)
  • Residues & TagsArg291~Arg544 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 97%
  • Isoelectric Point8.88
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  • Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) Packages (Simulation)
  • Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) Packages (Simulation)
  • RPA554Ra01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Pre-treatment with cardamonin protects against cisplatin-induced nephrotoxicity in rats: Impact on NOX-1, inflammation and apoptosisPubmed: 24211271
  • Apocynin protects against ethanol-induced gastric ulcer in rats by attenuating the upregulation of NADPH oxidases 1 and 4PubMed: 26522475
  • RESISTANCE OR AEROBIC TRAINING DECREASES BLOOD PRESSURE AND IMPROVES CARDIOVASCULARAUTONOMIC CONTROL AND OXIDATIVE STRESS IN HYPERTENSIVE MENOPAUSAL RATS.Pubmed:27339182
  • Indole-3- carbinol enhances sorafenib cytotoxicity in hepatocellular carcinoma cells: A mechanistic studypubmed:27612096
  • Indole-3-carbinol protects against cisplatin-induced acute nephrotoxicity: role of calcitonin gene-related peptide and insulin-like growth factor-1.pubmed:27417335
  • Camel Milk Ameliorates 5-Fluorouracil-Induced Renal Injury in Rats: Targeting MAPKs, NF-κB and PI3K/Akt/eNOS PathwaysPubmed:29694984
  • Camel milk attenuates methotrexate-induced kidney injury via activation of PI3K/Akt/eNOS signaling and intervention with oxidative aberrationsPubmed:29667662
  • Anti-inflammatory and cytoprotective effect of plant sterol and galactooligosaccharides enriched beverages in Caco-2 cellsPubmed: 31290324
  • NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotypePubmed: 33170835
  • Targeting oxidative stress, apoptosis, and autophagy by galangin mitigates cadmium-induced renal damage: Role of SIRT1/Nrf2 and AMPK/mTOR pathwaysPubmed:34999115
  • Targeting inflammation, autophagy, and apoptosis by troxerutin attenuates methotrexate-induced renal injury in ratsPubmed:34953450

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