Recombinant NADPH Oxidase 4 (NOX4) Mus musculus (Mouse) Recombinant protein

KOX; KOX-1; RENOX; Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Endoplasmic reticulum lumen
  • Molecular Mass 46.7kDa, Accurate 43kDa(Analysis of differences refer to the manual)
  • Residues & TagsGly210~Ser578 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 80%
  • Isoelectric Point8.7
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  • Recombinant NADPH Oxidase 4 (NOX4) Packages (Simulation)
  • Recombinant NADPH Oxidase 4 (NOX4) Packages (Simulation)
  • Recombinant NADPH Oxidase 4 (NOX4) Figure. Gene Sequencing (Extract)
  • RPB924Mu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Apocynin protects against ethanol-induced gastric ulcer in rats by attenuating the upregulation of NADPH oxidases 1 and 4PubMed: 26522475
  • Oxidative stress promotes benign prostatic hyperplasiaPubMed: 26417670
  • Effects of Single and Combined Losartan and Tempol Treatments on Oxidative Stress, Kidney Structure and Function in Spontaneously Hypertensive Rats with Early Course of Proteinuric Nephropathy.pubmed:27560781
  • Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4.pubmed:28431936
  • Chronic restraint stress induces esophageal fibrosis with enhanced oxidative stress in a murine model
  • NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotypePubmed: 33170835
  • Biphasic changes in TGF-β1 signaling drive NSAID-induced multi-organ damagePubmed: 32750407

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