Polyclonal Antibody to Angiotensin I Converting Enzyme (ACE)Homo sapiens (Human)Polyclonal antibody

CD143; ACE1; DCP1; ACEI; ACE-I; Kininase II; Angiotensin-Converting Enzyme; Peptidyl-Dipeptidase A; Dipeptidyl Carboxypeptidase 1; Angiotensin-converting enzyme, soluble form

  • Polyclonal Antibody to Angiotensin I Converting Enzyme (ACE)Package and Components
  • Polyclonal Antibody to Angiotensin I Converting Enzyme (ACE)Package and Components
  • Polyclonal Antibody to Angiotensin I Converting Enzyme (ACE)Figure. DAB staining on IHC-P; Samples: Human Kidney Tissue.
  • PAA004Hu01.jpgFigure. Western Blot; Sample: Recombinant ACE, Human.
  • Polyclonal Antibody to Angiotensin I Converting Enzyme (ACE)Figure. Western Blot; Sample: Human Lung Tissue.
  • CertificateISO9001: 2008, ISO13485: 2003 Registered

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against ACE. It has been selected for its ability to recognize ACE in immunohistochemical staining and western blotting.

USAGE

Western blotting: 1-5µg/mL
Immunocytochemistry in formalin fixed cells: 5-20µg/mL
Immunohistochemistry in formalin fixed frozen section: 5-20µg/mL
Immunohistochemistry in paraffin section: 5-20µg/mL
Enzyme-linked Immunosorbent Assay: 0.05-2µg/mL
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Reference

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  • Malaysian Journal of Medical SciencesEffect of Repeatedly Heated Palm Olein on Blood Pressure–Regulating Enzymes Activity and Lipid Peroxidation in RatsUsm: MJMS19120
  • Journal of Cancer TherapyPlasma Levels of Angiotensin-Converting Enzymes 1 and 2 and AGTR2 (T1247G and A5235G) Gene Polymorphisms Are Associated to Breast Cancer Progression.Scirp: Source
  • The American journal of clinical nutritionVascular function and atherosclerosis progression after 1 y of flavonoid intake in statin-treated postmenopausal women with type 2 diabetes: a double-blind randomized controlled trial.Pubmed: 23553151
  • Journal of Vascular SurgeryCathepsin G deficiency reduces periaortic calcium chloride injury-induced abdominal aortic aneurysms in mice Pubmed:25037606
  • Reprod Toxicol.?ACE2 activation by xanthenone prevents leptin-induced increases in blood pressure and proteinuria during pregnancy in Sprague-Dawley ratsPubmed:25205467
  • Chemical Research in ToxicologySub-chronic Toxicity and Cardiovascular Responses in Spontaneously Hypertensive Rats after Exposure to Multiwall Carbon Nanotubes by Intratracheal InstillationPubmed:25580880
  • Chem Biol InteractArsenic causes aortic dysfunction and systemic hypertension in rats: Augmentation of angiotensin II signalingPubMed: 26079204
  • Biomed Res IntProtective Effect of Enalapril against Methionine-Enriched Diet-Induced Hypertension: Role of Endoplasmic Reticulum and Oxidative StressPubMed: 26640794
  • Clinics (Sao Paulo)MechanismsPubMed: 26602523
  • Chemical Research in ToxicologySubchronic Toxicity and Cardiovascular Responses in Spontaneously Hypertensive Rats after Exposure to Multiwalled Carbon Nanotubes by Intratracheal InstillationPubMed: 25580880
  • Intensive Care Medicine Experimental Angiotensin converting enzymes in patients with acute respiratory distress syndromeContent: 3
  • Evid Based Complement Alternat Med.Garlic Attenuates Plasma and Kidney ACE-1 and AngII Modulations in Early Streptozotocin-Induced Diabetic Rats: Renal Clearance and Blood Pressure ImplicationsPubmed:27293465