Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)

THIL; ACAT; T2; MAT; Acetoacetyl Coenzyme A Thiolase
Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)
ACAT1 is a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.The 427-amino acid precursor had a molecular mass of 45.2 kD. The sequence included a 33-residue leader peptide and a 394-amino acid subunit of the mature enzyme, which had a molecular mass of 41.4 kD. In all 4 cell lines, the T2 mRNA had the same 1.7-kb transcript as that of the control; however, content was reduced in 2 cell lines and normal in the other 2. Human T2 is a homotetramer of 41-kD subunits.
Organism species: Homo sapiens (Human)
  • Protein RPD664Hu01Recombinant Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)Customize
  • AntibodyPAD664Hu01Polyclonal Antibody to Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)Customize
  • AntibodyMAD664Hu21Monoclonal Antibody to Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)Customize
  • Assay KitSED664HuELISA Kit for Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)Customize
  • Assay KitSCD664HuCLIA Kit for Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)Customize
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
  • Protein RPD664Ra01Recombinant Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)Customize
  • AntibodyPAD664Ra01Polyclonal Antibody to Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)Customize
  • AntibodyMAD664Ra21Monoclonal Antibody to Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)Customize
  • Assay KitSED664RaELISA Kit for Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)Customize
  • Assay KitSCD664RaCLIA Kit for Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)Customize
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