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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Cyclin Dependent Kinase 5 (CDK5)
PSSALRE
Recently Cdk5 has emerged as an essential kinase in sensory pathways. Recent reports of Pareek et al. from NIH suggest its necessity in pain signaling. CDK5 is required for proper development of the brain and to be activated, CDK5 must associate with CDK5R1 or CDK5R2. Unlike other cyclin dependent kinases, CDK5 does not also require phosphorylation on the T loop so that binding with the activator is sufficient to activate the kinase. Cdk5 is involved in the processes of neuronal maturation and migration, phosphorylating the key intracellular adaptor of the reelin signaling chain.Experiments performed on mice lacking p35, a necessary activator of cdk5 in early brain development, showed that the normal layering of neurons was reversed in the cortex.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPA739Mu01 Recombinant Cyclin Dependent Kinase 5 (CDK5) Customize
Antibodies PAA739Mu01 Polyclonal Antibody to Cyclin Dependent Kinase 5 (CDK5) Customize
MAA739Mu21 Monoclonal Antibody to Cyclin Dependent Kinase 5 (CDK5) Customize
Assay Kits SEA739Mu ELISA Kit for Cyclin Dependent Kinase 5 (CDK5) Customize
SCA739Mu CLIA Kit for Cyclin Dependent Kinase 5 (CDK5) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPA739Ra01 Recombinant Cyclin Dependent Kinase 5 (CDK5) Customize
Antibodies MAA739Ra21 Monoclonal Antibody to Cyclin Dependent Kinase 5 (CDK5) Customize
PAA739Ra01 Polyclonal Antibody to Cyclin Dependent Kinase 5 (CDK5) Customize
Assay Kits SEA739Ra ELISA Kit for Cyclin Dependent Kinase 5 (CDK5) In Stock
SCA739Ra CLIA Kit for Cyclin Dependent Kinase 5 (CDK5) Customize