Endothelial Cell Specific Molecule 1 (ESM1)
Endocan
Endothelial cell-specific molecule 1 is encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. The cDNA sequence contains an open reading frame of 552 nucleotides. The deduced 184-amino acid protein is cysteine rich with an N-terminal hydrophobic signal sequence. Expression of ESM1 was tested by Northern blot analysis and RT-PCR and was found to be constitutive in a HUVEC cell line, but not in any other cell line tested. Constitutive ESM1 expression in human tissue is restricted to the lung. Immunoblotting and immunoprecipitation identified a 20-kD protein.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC463Hu01 Recombinant Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Active protein APC463Hu01 Active Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Polyclonal antibody PAC463Hu01 Polyclonal Antibody to Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Monoclonal antibody MAC463Hu22 Monoclonal Antibody to Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Labelled antibody LAC463Hu71 Biotin-Linked Polyclonal Antibody to Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Monoclonal antibody MAC463Hu25 Monoclonal Antibody to Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Sandwich ELISA SEC463Hu ELISA Kit for Endothelial Cell Specific Molecule 1 (ESM1) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPC463Mu01 Recombinant Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Recombinant protein RPC463Mu02 Recombinant Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Polyclonal antibody PAC463Mu01 Polyclonal Antibody to Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Polyclonal antibody PAC463Mu02 Polyclonal Antibody to Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Sandwich ELISA SEC463Mu ELISA Kit for Endothelial Cell Specific Molecule 1 (ESM1) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPC463Ra01 Recombinant Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Polyclonal antibody PAC463Ra01 Polyclonal Antibody to Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Labelled antibody LAC463Ra71 Biotin-Linked Polyclonal Antibody to Endothelial Cell Specific Molecule 1 (ESM1) In Stock
- Sandwich ELISA SEC463Ra ELISA Kit for Endothelial Cell Specific Molecule 1 (ESM1) In Stock