Withdrawal Syndrome (WS)

Discontinuation syndrome

Withdrawal Syndrome (WS)

Alcohol withdrawal syndrome is a set of symptoms that can occur following a reduction in alcohol use after a period of excessive use.   Symptoms typically include anxiety, shakiness, sweating, vomiting, fast heart rate, and a mild fever. More severe symptoms may include seizures, seeing or hearing things that others do not, and delirium tremens (DTs). Alcohol withdrawal may occur in those who are alcohol dependent. This may occur following a planned or unplanned decrease in alcohol intake. The underlying mechanism involves a decreased responsiveness of GABA receptors in the brain. The withdrawal process is typically followed using the Clinical Institute Withdrawal Assessment of Alcohol Scale, revised (CIWA-Ar). test


Organism species: Mus musculus (Mouse)

Organism species: Rattus norvegicus (Rat)

Organism species: Oryctolagus cuniculus (Rabbit)