Nexilin (NEXN)

NELIN; F Actin Binding Protein

Nexilin (NEXN)
The name nexilin came from the Latin word nexilis, meaning 'bound together.' Full-length b-nexilin contains an N-terminal F-actin-binding domain (ABD), followed by a spacer, a coiled-coil region, a second ABD, and a long C-terminal tail. In comparison, s-nexilin lacks the N-terminal ABD and has an insertion in the C-terminal tail. Immunofluorescence microscopy revealed that both b-nexilin and s-nexilin colocalized with F-actin at focal contacts at the ends of stress fibers.
The nexilins did not localize to cell-cell junctions. Western blot analysis detected nexilin proteins with apparent molecular masses above 90 kD in rat brain, testis, and spleen and in cultured rodent fibroblasts. Neither protein was detected in liver, kidney, or epithelial cell lines.

Organism species: Homo sapiens (Human)

Organism species: Mus musculus (Mouse)

  • Recombinant protein RPH548Mu01 Recombinant Nexilin (NEXN) In Stock
  • Polyclonal antibody PAH548Mu01 Polyclonal Antibody to Nexilin (NEXN) In Stock
  • Customized Service n/a CLIA Kit for Nexilin (NEXN) CLIA Kit Customized Service Offer
  • Customized Service n/a ELISA Kit for Nexilin (NEXN) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

  • Recombinant protein RPH548Ra01 Recombinant Nexilin (NEXN) In Stock
  • Polyclonal antibody PAH548Ra01 Polyclonal Antibody to Nexilin (NEXN) In Stock
  • Customized Service n/a CLIA Kit for Nexilin (NEXN) CLIA Kit Customized Service Offer
  • Customized Service n/a ELISA Kit for Nexilin (NEXN) ELISA Kit Customized Service Offer