PTEN Induced Putative Kinase 1 (PINK1)

BRPK; PARK6; Parkinson Disease(Autosomal Recessive)6; Serine/threonine-protein kinase PINK1, mitochondrial
PTEN Induced Putative Kinase 1 (PINK1)
PINK1 encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.
The protein shares 43% and 31% sequence identity with Drosophila CG4523 and C. elegans EEED8.9, respectively. Northern blot analysis detected ubiquitous expression of a 2.7-kb transcript, with highest expression in heart, skeletal muscle, and testis. RT-PCR analysis showed that expression of PINK1 was decreased in ovarian tumors compared with corresponding normal tissues.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
  • Protein RPL057Ra01Recombinant PTEN Induced Putative Kinase 1 (PINK1)Customize
  • AntibodyPAL057Ra01Polyclonal Antibody to PTEN Induced Putative Kinase 1 (PINK1)Customize
  • AntibodyMAL057Ra21Monoclonal Antibody to PTEN Induced Putative Kinase 1 (PINK1)Customize
  • Assay KitSEL057RaELISA Kit for PTEN Induced Putative Kinase 1 (PINK1)Customize
  • Assay KitSCL057RaCLIA Kit for PTEN Induced Putative Kinase 1 (PINK1)Customize
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