Home  |   About us
ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Perforin 1 (PRF1)
FLH2; HPLH2; P1; PFP; Pore Forming Protein
Perforin is a cytolytic protein found in the granules of CD8 T-cells and NK cells. Perforin is a cytolytic protein found in the granules of Cytotoxic T lymphocytes (CTLs) and NK cells. Upon degranulation, perforin inserts itself into the target cell's plasma membrane, forming a pore. The lytic membrane-inserting part of perforin is the MACPF domain. This region shares homology with cholesterol-dependent cytolysins from Gram-positive bacteria. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPB317Hu01 Recombinant Perforin 1 (PRF1) In Stock
Antibodies MAB317Hu22 Monoclonal Antibody to Perforin 1 (PRF1) Customize
PAB317Hu01 Polyclonal Antibody to Perforin 1 (PRF1) In Stock
PAB317Hu71 Biotin-Linked Antibody to Perforin 1 (PRF1) Customize
PAB317Hu81 FITC-Linked Antibody to Perforin 1 (PRF1) Customize
Assay Kits SEB317Hu ELISA Kit for Perforin 1 (PRF1) In Stock
SCB317Hu CLIA Kit for Perforin 1 (PRF1) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPB317Mu01 Recombinant Perforin 1 (PRF1) In Stock
RPB317Mu02 Recombinant Perforin 1 (PRF1) Customize
Antibodies PAB317Mu01 Polyclonal Antibody to Perforin 1 (PRF1) In Stock
PAB317Mu02 Polyclonal Antibody to Perforin 1 (PRF1) Customize
PAB317Mu71 Biotin-Linked Antibody to Perforin 1 (PRF1) Customize
PAB317Mu81 FITC-Linked Antibody to Perforin 1 (PRF1) Customize
MAB317Mu21 Monoclonal Antibody to Perforin 1 (PRF1) Customize
Assay Kits SEB317Mu ELISA Kit for Perforin 1 (PRF1) In Stock
SCB317Mu CLIA Kit for Perforin 1 (PRF1) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPB317Ra01 Recombinant Perforin 1 (PRF1) Customize
Antibodies MAB317Ra21 Monoclonal Antibody to Perforin 1 (PRF1) Customize
PAB317Ra01 Polyclonal Antibody to Perforin 1 (PRF1) Customize
Assay Kits SEB317Ra ELISA Kit for Perforin 1 (PRF1) In Stock
SCB317Ra CLIA Kit for Perforin 1 (PRF1) Customize