Permeability Glycoprotein (Pgp)
CD243; ABCB1; ABC20; CLCS; GP170; MDR1; PGY1; P-Glycoprotein; Multidrug resistance protein 1; ATP-Binding Cassette,Sub-Family B(MDR/TAP),Member 1; Colchicin Sensitivity
P-glycoprotein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Organism species: Homo sapiens (Human)
- Recombinant protein RPB690Hu01 Recombinant Permeability Glycoprotein (Pgp) In Stock
- Recombinant protein RPB690Hu02 Recombinant Permeability Glycoprotein (Pgp) In Stock
- Eukaryotic protein EPB690Hu61 Eukaryotic Permeability Glycoprotein (Pgp) In Stock
- Polyclonal antibody PAB690Hu01 Polyclonal Antibody to Permeability Glycoprotein (Pgp) In Stock
- Monoclonal antibody MAB690Hu22 Monoclonal Antibody to Permeability Glycoprotein (Pgp) In Stock
- Labelled antibody LAB690Hu81 FITC-Linked Polyclonal Antibody to Permeability Glycoprotein (Pgp) In Stock
- Polyclonal antibody PAB690Hu02 Polyclonal Antibody to Permeability Glycoprotein (Pgp) In Stock
- Monoclonal antibody MAB690Hu21 Monoclonal Antibody to Permeability Glycoprotein (Pgp) In Stock
- Monoclonal antibody MAB690Hu23 Monoclonal Antibody to Permeability Glycoprotein (Pgp) In Stock
- Monoclonal antibody MAB690Hu24 Monoclonal Antibody to Permeability Glycoprotein (Pgp) In Stock
- Sandwich ELISA SEB690Hu ELISA Kit for Permeability Glycoprotein (Pgp) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPB690Mu02 Recombinant Permeability Glycoprotein (Pgp) In Stock
- Recombinant protein RPB690Mu01 Recombinant Permeability Glycoprotein (Pgp) In Stock
- Labelled antibody LAB690Mu81 FITC-Linked Polyclonal Antibody to Permeability Glycoprotein (Pgp) In Stock
- Labelled antibody LAB690Mu71 Biotin-Linked Polyclonal Antibody to Permeability Glycoprotein (Pgp) In Stock
- Polyclonal antibody PAB690Mu02 Polyclonal Antibody to Permeability Glycoprotein (Pgp) In Stock
- Polyclonal antibody PAB690Mu01 Polyclonal Antibody to Permeability Glycoprotein (Pgp) In Stock
- Sandwich ELISA SEB690Mu ELISA Kit for Permeability Glycoprotein (Pgp) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPB690Ra01 Recombinant Permeability Glycoprotein (Pgp) In Stock
- Polyclonal antibody PAB690Ra01 Polyclonal Antibody to Permeability Glycoprotein (Pgp) In Stock
- Sandwich ELISA SEB690Ra ELISA Kit for Permeability Glycoprotein (Pgp) In Stock