Prekallikrein (PK)
KLKB1; KLK3; Fletcher Factor; Kallikrein B,Plasma; Kininogenin; Plasma prekallikrein
Prekallikrein (PK), also known as Fletcher factor, is a 85,000 Mr serine protease that complexes with HK. Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain.
Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulfide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain.
Organism species: Homo sapiens (Human)
- Recombinant protein RPB801Hu01 Recombinant Prekallikrein (PK) In Stock
- Polyclonal antibody PAB801Hu01 Polyclonal Antibody to Prekallikrein (PK) In Stock
- Monoclonal antibody MAB801Hu22 Monoclonal Antibody to Prekallikrein (PK) In Stock
- Sandwich ELISA SEB801Hu ELISA Kit for Prekallikrein (PK) In Stock
Organism species: Mus musculus (Mouse)
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- Sandwich ELISA SEB801Mu ELISA Kit for Prekallikrein (PK) In Stock
Organism species: Rattus norvegicus (Rat)
- Eukaryotic protein EPB801Ra61 Eukaryotic Prekallikrein (PK) In Stock
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