UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)

UGT1; GNT1; UGT1A; UDPGT; HUG-BR1; UGT1-1; Bilirubin-specific UDPGT isozyme 1; UDP-glucuronosyltransferase 1-1
UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
UGT-1A is a uridine diphosphate glucuronyltransferase (UDP-glucuronosyltransferase, UDPGT), an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. The UGT1A1 gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
  • Protein RPG920Mu01Recombinant UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)Customize
  • AntibodyPAG920Mu01Polyclonal Antibody to UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)Customize
  • AntibodyMAG920Mu21Monoclonal Antibody to UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)Customize
  • Assay KitSEG920MuELISA Kit for UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)Customize
  • Assay KitSCG920MuCLIA Kit for UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)Customize
Organism species: Rattus norvegicus (Rat)
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