Canine Model for Embolic Cerebral Infarction (ECI) Canis familiaris; Canine (Dog) Disease model

ECI

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceCerebral infarction with emboli
  • Model Animal StrainsClosed group, general level, age 6 to 9 months old, weight: 6-10kg.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
  • Modeling Period4-6 weeks
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  • Canine Model for Embolic Cerebral Infarction (ECI) Packages (Simulation)
  • Canine Model for Embolic Cerebral Infarction (ECI) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

"Take the venous blood of the dog with a certain proportion of thrombin mixture, rapid inhalation of the inner diameter of 0.8 mm in the glass tube, placed in a vertical position in about 4 degrees, until the blood clot completely contracted through the carotid artery to the internal carotid artery segment, inject into the thrombus."

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±s), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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