Mouse Model for Elevated Glucocorticoid Disease (EGD) Mus musculus (Mouse) Disease model

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by tail suspension
  • Model Animal StrainsBalb/c Mice(SPF), healthy, male, age: 4~6weeks, body weight:18g~20g.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group(low,medium,high).
  • Modeling Period4-6 weeks
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  • Mouse Model for Elevated Glucocorticoid Disease (EGD) Packages (Simulation)
  • Mouse Model for Elevated Glucocorticoid Disease (EGD) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

The acute stress method is adopted.1) tail hanging method: the mice tail anus for fixed point 1.5 ~ 2.0 cm, to be suspended in the water, suspended from in rat nasal just water and degrees, tail hanging 4 hours .

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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