Rabbit Model for Thermal Injury (TI) Oryctolagus cuniculus (Rabbit) Disease model

Skin thermal injury ; Thermal burn; Scald

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by burnning
  • Model Animal StrainsBig ears white rabbit, healthy, male and female, weight 1.5-2.5kg.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
  • Modeling Period4-6 weeks
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  • Rabbit Model for Thermal Injury (TI) Packages (Simulation)
  • Rabbit Model for Thermal Injury (TI) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

"Weight 2.5 kg experimental rabbit 1 d before the experiment with 100 g/L sodium sulphide back coat off, can't help but drink 12 h before experiment, ether inhalation method of general anesthesia; the rabbit back and on both sides of the torso into 95 degrees thermostatic water hot 30 s, III degree burns 30% body surface area."

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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