Protein Kinase N2 (PKN2)

PRK2; Pak-2; PRKCL2; Protein Kinase C-Like 2; Protein-kinase C-related kinase 2; Serine/threonine-protein kinase N2; Cardiolipin-Activated Protein Kinase Pak2
Protein Kinase N2 (PKN2)
The cDNA sequence predicts a 984-amino acid polypeptide. Expression of this cDNA in COS cells produced a 130-kD protein product that was capable of autophosphorylation, indicating intrinsic kinase activity. Using Northern blot and RT-PCR analyses to examine expression patterns in a wide variety of tissues, Palmer et al. (1995) detected PRK2 expression in DX3 B-cell myeloma cells only. Yu et al. (1997) purified a protein kinase, termed PAK2, from rat liver and showed that the corresponding gene is the rat homolog of human PRK2. PAK2 has biochemical properties similar to, but distinct from PRK1/PAK1. PAK2 is activated by lipids, particularly cardiolipin.The International Radiation Hybrid Mapping Consortium mapped the PKN2 gene to chromosome 1
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
  • Protein RPB987Ra01Recombinant Protein Kinase N2 (PKN2)Customize
  • AntibodyPAB987Ra01Polyclonal Antibody to Protein Kinase N2 (PKN2)Customize
  • AntibodyMAB987Ra21Monoclonal Antibody to Protein Kinase N2 (PKN2)Customize
  • Assay KitSEB987RaELISA Kit for Protein Kinase N2 (PKN2)Customize
  • Assay KitSCB987RaCLIA Kit for Protein Kinase N2 (PKN2)Customize
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