Runt Related Transcription Factor 2 (RUNX2)

AML3; CBFA1; CCD1; OSF2; PEBP2A; Acute myeloid leukemia 3 ; Core-binding factor alpha-1; Osteoblast-specific transcription factor 2; Polyomavirus enhancer-binding protein 2 A
Runt Related Transcription Factor 2 (RUNX2)
Cbfa1/Runx2 is a key transcription factor associated with osteoblast differentiation.This protein is a member of the RUNX family of transcription factors and has a Runt DNA-binding domain. It is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Transcript variants of the gene that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.The RUNX2 transcription factor is the master regulator of osteoblast differentiation is required for chondrocyte hypertrophy .
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
  • Protein RPB011Ra01Recombinant Runt Related Transcription Factor 2 (RUNX2)Customize
  • AntibodyPAB011Ra01Polyclonal Antibody to Runt Related Transcription Factor 2 (RUNX2)Customize
  • AntibodyMAB011Ra21Monoclonal Antibody to Runt Related Transcription Factor 2 (RUNX2)Customize
  • Assay KitSEB011RaELISA Kit for Runt Related Transcription Factor 2 (RUNX2)Customize
  • Assay KitSCB011RaCLIA Kit for Runt Related Transcription Factor 2 (RUNX2)Customize
Leave your messages here

Welcome to our website. If you have any questions, please send a message to us.
We'll Feedback to you within 24 hours.Our work time is from AM 8:00 to PM 4:30 (U.S. Central Time)

  • Sales:sales@cloud-clone.us
  • After-sales:service@cloud-clone.us
  • Email:mail@cloud-clone.us
  • Close