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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Fibronectin Type III Domain Containing Protein 5 (FNDC5)
FRCP2; Irisin
FNDC5 contains an N-terminal signal peptide, a fibronectin type III domain, and a transmembrane domain. The 2 proteins share 60% identity in the FNIII domain and 86% in the transmembrane domain. Northern blot analysis of multiple mouse tissues detected highest expression of Fndc5 in adult brain and heart, and low expression in lung, skeletal muscle, and testis. Northern blot analysis of mouse embryonic mRNA first detected Fndc5 expression at embryonic day 11, with strongest expression at E15 and decreasing expression at E17. In situ hybridization demonstrated expression of Fndc5 in the fore- and midbrain, as well as in the brachial arches and the heart. Overexpression of a GFP-Fndc5 fusion protein in COS cells showed localization predominantly in the endoplasmic reticulum, with small amounts in the plasma membrane.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPN576Hu01 Recombinant Fibronectin Type III Domain Containing Protein 5 (FNDC5) In Stock
RPN576Hu02 Recombinant Fibronectin Type III Domain Containing Protein 5 (FNDC5) In Stock
Antibodies PAN576Hu01 Polyclonal Antibody to Fibronectin Type III Domain Containing Protein 5 (FNDC5) In Stock
PAN576Hu02 Polyclonal Antibody to Fibronectin Type III Domain Containing Protein 5 (FNDC5) In Stock
PAN576Hu71 Biotin-Linked Antibody to Fibronectin Type III Domain Containing Protein 5 (FNDC5) Customize
MAN576Hu21 Monoclonal Antibody to Fibronectin Type III Domain Containing Protein 5 (FNDC5) Customize
Assay Kits SEN576Hu ELISA Kit for Fibronectin Type III Domain Containing Protein 5 (FNDC5) In Stock
SCN576Hu CLIA Kit for Fibronectin Type III Domain Containing Protein 5 (FNDC5) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPN576Mu01 Recombinant Fibronectin Type III Domain Containing Protein 5 (FNDC5) Customize
RPN576Mu02 Recombinant Fibronectin Type III Domain Containing Protein 5 (FNDC5) Customize
Antibodies PAN576Mu01 Polyclonal Antibody to Fibronectin Type III Domain Containing Protein 5 (FNDC5) In Stock
PAN576Mu02 Polyclonal Antibody to Fibronectin Type III Domain Containing Protein 5 (FNDC5) Customize
MAN576Mu21 Monoclonal Antibody to Fibronectin Type III Domain Containing Protein 5 (FNDC5) Customize
Assay Kits SEN576Mu ELISA Kit for Fibronectin Type III Domain Containing Protein 5 (FNDC5) In Stock
SCN576Mu CLIA Kit for Fibronectin Type III Domain Containing Protein 5 (FNDC5) Customize