Vinculin (VCL)

MVCL; Metavinculin
Vinculin (VCL)
In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Its sequence is 20-30% homologous to α-catenin, which serves a similar function.
Vinculin is a 117 kDa cytoskeletal protein with 1066 amino acids. The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment. Vinculin consists of a globular head domain that contains binding sites for talin and α-actinin as well as a tyrosine phosphorylation site, while the tail region contains binding sites for F-actin, paxillin and lipids.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
  • Protein RPB839Ra01Recombinant Vinculin (VCL)Customize
  • AntibodyPAB839Ra01Polyclonal Antibody to Vinculin (VCL)Customize
  • AntibodyMAB839Ra21Monoclonal Antibody to Vinculin (VCL)Customize
  • Assay KitSEB839RaELISA Kit for Vinculin (VCL)Customize
  • Assay KitSCB839RaCLIA Kit for Vinculin (VCL)Customize
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