Polyclonal Antibody to Corticosterone (Cort) Pan-species (General) Polyclonal antibody

Corticosrone

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen CPA540Ge11-BSA Conjugated Corticosterone (Cort)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/ml
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  • Polyclonal Antibody to Corticosterone (Cort) Packages (Simulation)
  • Polyclonal Antibody to Corticosterone (Cort) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against Cort. It has been selected for its ability to recognize Cort in immunohistochemical staining and western blotting.

Usage

Enzyme-Linked Immune Sorbent Assay: 4.18ug/ml
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • Intracerebroventricular injection of leukotriene B4 attenuates antigen-induced asthmatic response via BLT1 receptor stimulating HPA-axis in sensitized rats.PubMed: 20403205
  • Effects of Gypenosides on Acute Stress in MicePapersearch: Source
  • Role of adrenomedullin in the cerebrospinal fluid-contacting nucleus in the modulation of immobilization stressPubmed:25911494
  • Sick Sinus Syndrome May Attribute to the Decrease of ?±-klotho Protein in MiceCom:Source
  • Organ-Specific Activation of the Gastric Branch of the Efferent Vagus Nerve by Ghrelin in Urethane-Anesthetized RatsPubmed:24366191
  • Regulation of corticosterone secretion is modified by PFOS exposure at different levels of the hypothalamic–pituitary–adrenal axis in adult male ratsPubmed:24440345
  • Restraint stress alters immune parameters and induces oxidative stress in the mouse uterus during embryo implantationPubmed:25238024
  • Diabetes alters the blood glucose response to ketamine in streptozotocin-diabetic ratsPubMed: 26379948
  • Trivalent Chromium Attenuated Corticosterone Secretion and Actions in Adrenocorticotropic Hormone-Stimulated RatsIn_Press: 15-058.Pdf
  • Ameliorating effects of gypenosides on chronic stress-induced anxiety disorders in micePubMed: 26370834
  • Rats with differential self-grooming expression in the elevated plus-maze do not differ in anxiety-related behaviorsPubMed: 26142783
  • Improvement of oral contraceptive-induced glucose dysreCavia (Guinea pig )lation and dyslipidemia by valproic acid is independent of circulating corticosteronePubmed:26855320
  • Activation of cardiac renin–angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorderPubmed:26934364
  • Electroacupuncture reCavia (Guinea pig )late hypothalamic–pituitary–adrenal axis and enhance hippocampal serotonin system in a rat model of depressionPubmed:26773866
  • Moxibustion upreCavia (Guinea pig )lates hippocampal progranulin expression.Pubmed:27212922
  • Lycopene ameliorates atrazine-induced oxidative damage in adrenal cortex of male rats by activation of the Nrf2/HO-1 pathwayPubmed:27102619
  • Apelin-13 exerts antidepressant-like and recognition memory improving activities in stressed ratsPubmed:26853763
  • Dopamine D2-like receptors modulate freezing response, but not the activation of HPA axis, during the expression of conditioned fear.pubmed:27766352
  • Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus.pubmed:28161195
  • Effects of (-)-Sesamin on Chronic Stress-Induced Anxiety Disorders in Micepubmed:27995494
  • Role of serotonin in the intestinal mucosal epithelium barrier in weaning mice undergoing stress-induced diarrheapubmed:29260435
  • The Role of Psychological Stress on Heart Autophagy in Mice With Heart Failurepubmed:28691995
  • Environmental perturbation of the circadian clock during pregnancy leads to transgenerational mood disorder-like behaviors in micepubmed:28974783
  • Role of serotonin on the intestinal mucosal immune response to stress-induced diarrhea in weaning micepubmed:28633646
  • Anxiety-like but not despair-like behaviors are further aggravated by chronic mild stress in the early stages of APPswe/PS1dE9 transgenic micedoi.org/10.1101/202283
  • Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.pubmed:28959186
  • Effects of n-3 PUFA enriched and n-3 PUFA deficient diets in naïve and Aβ-treated female ratsPubmed:30028991
  • Impact of Perfluorooctane Sulfonate on Reproductive Ability of Female Mice through Suppression of Estrogen Receptor a-Activated Kisspeptin Neurons10.1093:toxsci
  • Multigenerational effects of dietary macronutrients intake on the metabolic phenotype of male Wistar rats10.1016:j.nut.2018.06.008
  • Depressive-and anxiety-like phenotypes in young adult APPSwe/PS1dE9 transgenic mice with insensitivity to chronic mild stressPubmed:30012417
  • Blockade of AT1 type receptors for angiotensin II prevents cardiac microvascular fibrosis induced by chronic stress in Sprague–Dawley ratsPubmed:29676198
  • Differential Effects of Brain Death on Rat Microcirculation and Intestinal Inflammation: Female MalePubmed:29737476
  • Curcumin attenuates chronic intermittent hypoxia-induced brain injuries by inhibiting AQP4 and p38 MAPK pathwayPubmed:29758366
  • Chronic treatment with dexamethasone alters clock gene expression and melatonin synthesis in rat pineal gland at nightPubmed:30046256
  • Tannins from fruits attenuates GABA antagonist‐induced anxiety‐like behaviour modulation of neurotransmittersPubmed: 30198561
  • Expression of Hif-1α, Nf-κb, and Vegf Genes in the Liver and Blood Serum Levels of HIF-1α, Erythropoietin, VEGF, TGF-β, 8-Isoprostane, and Corticosterone in Wistar Rats with High and Low Resistance to Hypoxia. Corticosterone in …Pubmed: 30353332
  • HMGB1-Mediated Differential Response on Hippocampal Neurotransmitter Disorder and Neuroinflammation in Adolescent Male and Female Mice following Cold ExposurePubmed: 30476565
  • Establishment and evaluation of a novel mouse model of peri/postmenopausal depressionDoi: 10.1016/j.heliyon.2019.e01195
  • Mice lacking Casp1, Ifngr and Nos2 genes exhibit altered depressive-and anxiety-like behaviour, and gut microbiome compositionPubmed: 31015500
  • Antidepressant-like effects of dietary gardenia blue pigment derived from genipin and tyrosineDoi: 10.1039/C9FO00480G
  • Synaptic structure and alterations in the hippocampus in neonatal rats exposed to lipopolysaccharidePubmed: 31288048
  • Contribution of DNA methylation in chronic stress–induced cardiac remodeling and arrhythmias in micePubmed: 31431066
  • MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression ModelPubmed: 31540304
  • Mice with nucleus tractus solitarius injury induced by chronic restraint stress present impaired ability to raise blood glucose and glucagon levels when blood glucose …Pubmed: 32249244
  • GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and …Pubmed: 33166810
  • Anxiolytic and Anti‑depressive Like Effects of Translocator Protein (18 kDa) Ligand YL‑IPA08 in a Rat Model of Postpartum DepressionPubmed: 32383026
  • Pathophysiological Changes in Female Rats with Estrous Cycle Disorder Induced by Long-Term Heat StressPubmed: 32685488
  • Neurobiological determinants of depressive-like symptoms in rodents
  • Exposure to eagle owl feces induces anti-predator behavior, physiology, and hypothalamic gene responses in a subterranean rodent, the plateau zokor (Eospalax …
  • Empagliflozin improves chronic hypercortisolism-induced abnormal myocardial structure and cardiac function in mice33294147
  • Water-Soluble Carbon Dots in Cigarette Mainstream Smoke: Their Properties and the Behavioural, Neuroendocrinological, and Neurotransmitter Changes They ¡­33762821
  • O-GlcNAc/Akt pathway regulates glucose metabolism and reduces apoptosis in liver of piglets with acute cold stress33651993
  • Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats33785408
  • A Famous Chinese Medicine Formula: Yinhuo Decoction Antagonizes the Damage of Corticosterone to PC12 Cells and Improves Depression by Regulating …Pubmed:35281603
  • Monochromatic blue light not green light exposure is associated with continuous light-induced hepatic steatosis in high fat diet fed-mice via oxidative stressPubmed:35588616

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