FITC-Linked Polyclonal Antibody to Gamma-Aminobutyric Acid (gABA) Pan-species (General) Labelled antibody

4-Aminobutyric Acid

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Overview
Properties
  • SourceAntibody labeling
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelFITC
  • Original Antibody PAA900Ge01-Polyclonal Antibody to Gamma-Aminobutyric Acid (gABA)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 500µg/mL
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  • FITC-Linked Polyclonal Antibody to Gamma-Aminobutyric Acid (gABA) Packages (Simulation)
  • FITC-Linked Polyclonal Antibody to Gamma-Aminobutyric Acid (gABA) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against gABA. It has been selected for its ability to recognize gABA in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Pan-species (General)

Giveaways

Citations

  • Effect of sub-acute exposure to acrylamide on GABAergic neurons and astrocytes in weaning rat cerebellumPubMed: 21444355
  • Expression of the neuron-specific potassium chloride cotransporter KCC2 in adult rat cochlear.PubMed: 18577424
  • Decreased Epidermal Growth Factor (EGF) Associated with HMGB1 and Increased Hyperactivity in Children with AutismPubMed: PMC3623607
  • Correlation Between Hepatocyte Growth Factor (HGF) and Gamma-Aminobutyric Acid (GABA) Plasma Levels in Autistic ChildrenPubMed: PMC3694825
  • Decreased Hepatocyte Growth Factor (HGF) and Gamma Aminobutyric Acid (GABA) in Individuals with Obsessive-Compulsive Disorder (OCD)PubMed: PMC3762604
  • Renal Denervation Improves the Baroreflex and GABA System in Chronic Kidney Disease-induced Hypertensionpubmed:27917928
  • Sex differences in the glutamate signaling pathway in juvenile ratsPubmed:28861894
  • A novel homozygous mutation in GAD1 gene described in a schizophrenic patient impairs activity and dimerization of GAD67 enzymePubmed: 30341396
  • Aucubin Alleviates Seizures Activity in Li-Pilocarpine-Induced Epileptic Mice: Involvement of Inhibition of Neuroinflammation and Regulation of NeurotransmissionPubmed: 30666488
  • Differentiation of human glioblastoma U87 cells into cholinergic neuronPubmed: 30928478
  • Glutamate Signaling Defects in Propionic Acid Orally Administered to Juvenile Rats as an Experimental Animal Model of Autism
  • Effect of gamma radiation on combination therapy of certain antiepileptic drugs in rats.
  • Antiepileptic effects of exogenous β‑hydroxybutyrate on kainic acid‑induced epilepsyPubmed: 33101467
  • Dementia model mice exhibited improvements of neuropsychiatric symptoms as well as cognitive dysfunction with neural cell transplantation33828024
  • Age-dependent neurological phenotypes in a mouse model of PRRT2-related diseases34101060
  • Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission34475508
  • Adaptogenic potential of ginsenosides against domoic acid‐induced toxicity by regulating neuronal stress and kinate receptors: Ex vivo and in silico studiesPubmed:35102569

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