Monoclonal Antibody to Prostaglandin E2 (PGE2)
PG-E2
Overview
Properties
- Product No.MAA538Ge22
- Organism SpeciesPan-species (General) Same name, Different species.
- ApplicationsELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
If the antibody is used in flow cytometry, please check FCM antibodies.
Research use only - DownloadInstruction Manual
- CategoryMetabolic pathwayInfection immunityEndocrinologyHormone metabolism
- SourceMonoclonal antibody preparation, Host Mouse
- Ig Isotype IgG2b Kappa, Clone Number C7
- PurificationProtein A + Protein G affinity chromatography
- LabelNone
- Immunogen CPA538Ge11-BSA Conjugated Prostaglandin E2 (PGE2)
- Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
- TraitsLiquid, Concentration 0.38mg/ml
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Specifity
The antibody is a mouse monoclonal antibody raised against PGE2. It has been selected for its ability to recognize PGE2 in ELISA and CLIA.
Usage
Immunohistochemistry: 5-20µg/mL;
Immunofluorescence:5-20µg/mL;
Optimal working dilutions must be determined by end user.
Storage
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Giveaways
Increment services
Citations
- Evidence for the complementary and synergistic effects of the three-alkaloid combination regimen containing berberine, hypaconitine and skimmianine on the ulcerative colitis rats induced by trinitrobenzene-sulfonic acidScienceDirect: S0188440910001049
- Celecoxib Ameliorates Portal Hypertension of the Cirrhotic Rats through the Dual Inhibitory Effects on the Intrahepatic Fibrosis and AngiogenesisPubMed: PMC3724827
- Lipid mediators in plasma of autism spectrum disordersPubMed: PMC3557222
- Interleulin-17 and Prostaglandin E2 Are Involved in Formation of an M2 Macrophage-dominant Microenvironment in Lung CancerPubMed: PMC3378786
- Artesunate exerts an anti-immunosuppressive effect on cervical cancer by inhibiting PGE2 production and Foxp3 expression.Pubmed: 24446394
- Multitargeted protective effect of Abacopteris penangiana against carrageenan-induced chronic prostatitis in rats.Pubmed: 24211397
- Celecoxib attenuates hepatic cirrhosis through inhibition of epithelial-to-mesenchymal transition of hepatocytesPubmed:24909904
- Valproic acid protects septic mice from renal injury by reducing the inflammatory responsePubmed:24948542
- Alpha-lipoic acid exerts anti-inflammatory effects on lipopolysaccharide-stimulated rat mesangial cells via inhibition of nuclear factor kappa B (NF-κB) signaling pathway.Pubmed:24962643
- Somatostatin prevents lipopolysaccharidePubMed: 25777539
- Celecoxib enhanced the cytotoxic effect of cisplatin in drug-resistant human gastric cancer cells by inhibition of cyclooxygenase-2PubMed: 26407653
- Penehyclidine Hydrochloride Preconditioning Provides Cardioprotection in a Rat Model of Myocardial Ischemia/Reperfusion InjuryPubMed: 26632817
- Mesenchymal stromal cell-dependent reprogramming of Kupffer cells is mediated by TNF-α and PGE9 and is crucial for liver transplant tolerancePubMed: 25982596
- Effects of morphine on the expression of cytokines and inflammatory mediators in a rabbit model of endotoxin-induced experimental uveitisPubMed: 26677041
- Effects of different ventilation strategies on exhaled nitric oxide in geriatric abdominal surgeryPubMed: 25719610
- Artemisinin inhibits the proliferation, migration, and inflammatory reaction induced by tumor necrosis factor-伪 in vascular smooth muscle cells through nuclear factor kappa B pathwayPubMed: 25575733
- Prostaglandin E2 (PGE2) promotes proliferation and invasion by enhancing SUMO-1 activity via EP4 receptor in endometrial cancerPubmed:27230680
- IL-23/Th17 axis is not influenced by TNF-blocking agents in ankylosing spondylitis patientsPubmed:26912133
- Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axisPubmed:27058422
- Inhibition of cyclooxygenase-2 alleviates liver cirrhosis via improvement of the dysfunctional Cavia (Guinea pig )t-liver axis in ratsPubmed:27056726
- Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis.pubmed:27058422
- Dietary Arachidonic Acid Has a Time-Dependent Differential Impact on Adipogenesis Modulated via COX and LOX Pathways in Grass Carp Ctenopharyngodon idellus.pubmed:27747453
- Role of cyclooxygenase-mediated metabolites in lipid metabolism and expression of some immune-related genes in juvenile grass carp (Ctenopharyngodon idellus) fed arachidonic acid.pubmed:28012026
- Metformin inhibits castration-induced EMT in prostate cancer by repressing COX2/PGE2/STAT3 axis.pubmed:28043910
- Identification of Biomarkers of Impaired Sensory Profiles among Autistic Patients.pubmed:27824861
- A Zinc Morpholine Complex Prevents HCl/Ethanol-Induced Gastric Ulcers in a Rat Model.pubmed:27460157
- Downregulation of HOTAIR Expression Mediated Anti-Metastatic Effect of Artesunate on CervicalCancer by Inhibiting COX-2 Expression.pubmed:27736969
- Flavonoids from sea buckthorn inhibit the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through the MAPK and NF-κB pathways.pubmed:28256654
- Increased Chondrogenic Potential of Mesenchymal Cells From Adipose Tissue Versus Bone Marrow‐Derived Cells in Osteoarthritic In Vitro Modelspubmed:27739057
- Flavonoids from sea buckthorn inhibit the lipopolysaccharide-induced inflammatory response in RAW264. 7 macrophages through the MAPK and NF-κB …DOI:10.1039/C6FO01873D
- Sea cucumber saponins liposomes ameliorate obesity-induced inflammation and insulin resistance in high-fat diet-fed micepubmed:29292463
- Ultraviolet A photosensitivity profile of dexchlorpheniramine maleate and promethazine-based creams: Anti-inflammatory,antihistaminic, and skin barrier protection propertiesDOI: 10.1111/jocd.12349
- Chemical composition of Cyclocarya paliurus polysaccharide and inflammatory effects in lipopolysaccharide-stimulated RAW264.7 macrophagepubmed:29032210
- Activation of PGE2/EP2 and PGE2/EP4 signaling pathways positively regulate the level of PD‑1 in infiltrating CD8+ T cells in patients with lung cancerpubmed:29285200
- Role of cyclooxygenase-mediated metabolites in lipid metabolism and expression of some immune-related genes in juvenile grass carp (Ctenopharyngodon idellus) fed arachidonic acid10.1007/s10695-016-0326-z
- Metformin Inhibits Prostate Cancer Progression by Targeting Tumor-Associated Inflammatory InfiltrationPubmed:30012567
- Differences in water soluble non-digestible polysaccharides and anti-inflammatory activities of fruiting bodies from two cultivated Xylaria nigripes strainsPubmed:29763701
- A Novel Role of Irbesartan in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats: Targeting DDAH/ADMA and EGFR/ERK SignalingPubmed:29523851
- Steroidal alkaloid solanine A from Linn. exhibits anti-inflammatory activity in lipopolysaccharide/interferon γ-activated murine macrophages and …Pubmed:29890469
- Polar extract of protects cartilage homeostasis: possible mechanism of actionPubmed:29313174
- Impaired lipid metabolism markers to assess the risk of neuroinflammation in autism spectrum disorderPubmed:29569150
- Phytochemical evaluation and anti-hemorrhoidal activity of bark of Acacia ferruginea DC10.1016:j.jtcme.2018.02.003
- Loganin prevents BV‐2 microglia cells from Aβ‐induced inflammation via regulating TLR4/TRAF6/NF‐κB axisPubmed: 30288860
- Multiple aPDT sessions on periodontitis in rats treated with chemotherapy: Histomorphometrical, Immunohistochemical, Imunological and Microbiological AnalysesPubmed: 30468900
- The anti-inflammatory and anti-oxidative effects of conbercept in treatment of macular edema secondary to retinal vein occlusionPubmed: 30558792
- Seasonal variations in hormones and enzymes of seminal plasma and its relationship with semen quality in crossbred cattle bullsDoi: 10.1080/09291016.2018.1548873
- Resveratrol enhances the protective effects of JBP485 against indomethacin-induced rat intestinal damage in vivo and vitro through up-regulating …Pubmed: 30590313
- Chandrasekaran Chinampudur Velusami, Edwin Jothie Richard &
- Adipose Tissue-Derived Mesenchymal Stem Cell Modulates the Immune Response of Allergic Rhinitis in a Rat ModelPubmed: 30781605
- Gastroprotective activity of a novel Schiff base derived dibromo substituted compound against ethanol-induced acute gastric lesions in ratsPubmed: 30770761
- Dihydrotestosterone synthesis in the sheep corpus luteum and its potential mechanism in luteal regressionPubmed: 30671954
- Maged Mohamed Abd-Elhakim Barakat, Noha Ahmed El-Boghdady, Ebtehal Kamal Eldin Farrag, Ataa Abdelhalim Said and Sylvia Edward Shaker
- Protective and Curative Effects of Bombax ceiba Flower and Ziziphus spina christi Fruit Extracts on Gastric Ulcer
- Chlorogenic Acid Attenuates Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice through MAPK/ERK/JNK Pathway
- 1, 25-(OH) 2D3 protects Schwann cells against advanced glycation end products-induced apoptosis through PKA-NF-κB pathwayPubmed: 30928409
- Increased expression of TRPV1 in patients with acute or chronic cough after lung cancer surgeryPubmed: 30883022
- Melatonin attenuates expression of cyclooxygenase-2 (COX-2) in activated microglia induced by lipopolysaccharide (LPS)Pubmed: 31081481
- Total flavonoids from sea buckthorn ameliorates lipopolysaccharide/cigarette smoke‐induced airway inflammationPubmed: 31209984
- Antidepressant-like effects of dietary gardenia blue pigment derived from genipin and tyrosineDoi: 10.1039/C9FO00480G
- Synergistic effect of sea cucumber saponin and EPA-enriched phospholipids on insulin resistance in high-fat diet-induced obese micePubmed: 31199413
- Polydatin ameliorates chemotherapy-induced cognitive impairment (chemobrain) by inhibiting oxidative stress, inflammatory response, and apoptosis in ratsPubmed: 31992173
- Management of Citrus sinensis peels for protection and treatment against gastric ulcer induced by ethanol in ratsPubmed: 32319821
- Intravitreal conbercept improves outcome of proliferative diabetic retinopathy through inhibiting inflammation and oxidative stressPubmed: 33227274
- Dietary Supplementation of Foxtail Millet Ameliorates Colitis-Associated Colorectal Cancer in Mice via Activation of Gut Receptors and Suppression of the STAT3 …Pubmed: 32784751
- The Efficacy of Processing Strategies on the Gastroprotective Potentiality of Chenopodium quinoa SeedsPubmed: 32549800
- FADS1 promotes the progression of laryngeal squamous cell carcinoma through activating AKT/mTOR signalingPubmed: 32332698
- Effect of Lonicerae japonicae Flos Carbonisata-Derived Carbon Dots on Rat Models of Fever and Hypothermia Induced by LipopolysaccharidePubmed: 32606669
- Echinacea polysaccharide attenuates lipopolysaccharide‑induced acute kidney injury via inhibiting inflammation, oxidative stress and the MAPK signaling pathway
- Inflammation Mediators Regulate the Microbiota Resistance to Adverse Factors33222085
- Fenretinide regulates macrophage polarization to protect against experimental colitis induced by dextran sulfate sodium33380244
- Bromelain reduced pro-inflammatory mediators as a common pathway that mediate antinociceptive and anti-anxiety effects in sciatic nerve ligated Wistar rats33432004
- Inhibition of cyclooxygenase©\2 enhanced intestinal epithelial homeostasis via suppressing ¦Â©\catenin signalling pathway in experimental liver fibrosis34145945
- Assessment of Galectin-1, Galectin-3, and PGE2 Levels in Patients with COVID-1933790073
- Effect of a Proprietary Herbal Product" Arthrocon" on some Synovial Fluid and Serum Biomarkers in Horses with Naturally Occurring Osteoarthritis
- Induction of apoptosis in activated RAW 264.7 cells and inhibition of pro-inflammatory mediators in rat air pouch by ethylacetate fraction of Ocimum gratissimum leaves
- Novel 1, 3, 4-Oxadiazole Derivatives of Pyrrolo [3, 4-d] Pyridazinone Exert Anti-Inflammatory Activity without Acute Gastrotoxicity in the Carrageenan-Induced …34754217
- Anti‑inflammation treatment for protection of hepatocytes and amelioration of hepatic fibrosis in rats34584558
- Indole-linked 1, 2, 3-triazole derivatives efficiently modulate COX-2 protein levels in human THP-1 monocytes by suppressing AGE-ROS-NF-kβ nexusPubmed:34990649
- The ameliorative effects of cinnamon oil against ethanol-induced gastric ulcer in rats by regulating oxidative stress and promoting angiogenesisPubmed:35290563
- Suppression of COX-2/PGE2 levels by carbazole-linked triazoles via modulating methylglyoxal-AGEs and glucose-AGEs–Induced ROS/NF-κB signaling in monocytesPubmed:35640822