Monoclonal Antibody to Reverse Triiodothyronine (rT3) Pan-species (General) Monoclonal antibody

RT3; r-T3; Reverse T3;(2S)-2-Amino-3-[4-(4-Hydroxy-3,5-Diiodophenoxy)-3-Iodophenyl]propanoic Acid; 3,3',5'-Triiodo-L-thyronine

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG2b Kappa, Clone Number C2
  • PurificationProtein A + Protein G affinity chromatography
  • LabelNone
  • Immunogen CPC022Ge11-BSA Conjugated Reverse Triiodothyronine (rT3)
  • Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/mL
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  • Monoclonal Antibody to Reverse Triiodothyronine (rT3) Packages (Simulation)
  • Monoclonal Antibody to Reverse Triiodothyronine (rT3) Packages (Simulation)
  • Monoclonal Antibody to Reverse Triiodothyronine (rT3) Competitive inhibition ELISA;
    Coated protein: rT3 conjugated to OVA (Catalog:CPC022Ge21);
    Standard:Series Diluted rT3;
    Primary Ab: 1.23µg/ml Mouse Anti rT3 Antibody;
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-mouse IgG
    PolyclonalAntibody (Catalog: SAA544Rb19)
    IC50=10ng/ml
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against rT3. It has been selected for its ability to recognize rT3 in ELISA and CLIA.

Usage

Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • N-Acetylcysteine Administration Prevents Nonthyroidal Illness Syndrome in Patients With Acute Myocardial Infarction: A Randomized Clinical TrialPubmed:25148231
  • Untersuchungen zum Schilddrüsenstoffwechsel der Milchkuh in Abhängigkeit des Laktations-, Reproduktions- und Gesundheitsstatusdissertations:steinhoffl_ws16.pdf
  • Inflammation severely alters thyroid hormone signaling in the central nervous system duringexperimental allergic encephalomyelitis in rat: Direct impact on OPCs differentiation failure.pubmed:27404574
  • A thyroid hormone network exists in synovial fibroblasts of rheumatoid arthritis and osteoarthritis patientsPubmed: 31519956

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