17-Beta-Hydroxysteroid Dehydrogenase Type 11 (HSD17b11)
DHRS8; PAN1B; RETSDR2; Estradiol 17-Beta-Dehydrogenase 11; Dehydrogenase/Reductase(SDR family)Member 8; Retinal Short-Chain Dehydrogenase/Reductase 2
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Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones. The deduced 300-amino acid protein has a potential N-glycosylation site at residue 228. The 5-prime UTR of the cDNA has a polymorphic adenosine repeat. high 17-beta-HSDXI expression in pancreas, kidney, liver, lung, adrenal gland, ovary, and heart. strong expression in steroidogenic cells, such as syncytiotrophoblasts, sebaceous gland, Leydig cells, and granulosa cells of the dominant follicle and corpus luteum. Expression in fetal adrenal gland increased after birth.In the eye, PAN1B was detected in nonpigmented epithelium of the ciliary body, with lower expression in the inner nuclear layer of the retina. Expression was also detected in normal adrenal cortex, granulosa cells, paraluteal cells, Leydig cells, and syncytiotrophoblasts.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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- Customized Service n/a CLIA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 11 (HSD17b11) CLIA Kit Customized Service Offer
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Organism species: Rattus norvegicus (Rat)
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- Customized Service n/a Polyclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 11 (HSD17b11) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 11 (HSD17b11) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 11 (HSD17b11) ELISA Kit Customized Service Offer