5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)
CblG; MS; MeSe; MetH Methionine Synthase; Vitamin-B12 dependent methionine synthase
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The remethylation of homocysteine to form methionine is catalyzed by the cytoplasmic enzyme 5-methyltetrahydrofolate-homocysteine S-methyltransferase (EC 2.1.1.13), which is also called methionine synthase. This enzyme requires methylcobalamin (MeCbl), a derivative of cobalamin, or vitamin B12, for activity.The patient was a 6-month-old girl with mental retardation, megaloblastic anemia, and high folate activity in the serum and red cells.
For this reason and also because rodent and human forms of the enzyme were electrophoretically distinguishable, these workers could use binding to identify the presence of human methyltransferase (MTR) in rodent-human somatic cell hybrids. By this approach, they assigned the methyltransferase gene to chromosome 1.
Organism species: Homo sapiens (Human)
- Recombinant protein RPG462Hu01 Recombinant 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) In Stock
- Monoclonal antibody MAG462Hu21 Monoclonal Antibody to 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) In Stock
- Polyclonal antibody PAG462Hu01 Polyclonal Antibody to 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) In Stock
- Sandwich ELISA SEG462Hu ELISA Kit for 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPG462Mu01 Recombinant 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) In Stock
- Customized Service n/a Monoclonal Antibody to 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR) ELISA Kit Customized Service Offer