ATP Binding Cassette Transporter C2 (ABCC2)
CMOAT1; ABC30; CMOAT; DJS; MRP2; cMRP; Canalicular Multispecific Organic Anion transporter 1; Canalicular multidrug resistance protein; Multidrug resistance-associated 2
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ABCC2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).his protein is a member of the MRP subfamily, which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells.Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.
Organism species: Homo sapiens (Human)
- Recombinant protein RPD622Hu01 Recombinant ATP Binding Cassette Transporter C2 (ABCC2) In Stock
- Polyclonal antibody PAD622Hu01 Polyclonal Antibody to ATP Binding Cassette Transporter C2 (ABCC2) In Stock
- Monoclonal antibody MAD622Hu21 Monoclonal Antibody to ATP Binding Cassette Transporter C2 (ABCC2) In Stock
- Sandwich ELISA SED622Hu ELISA Kit for ATP Binding Cassette Transporter C2 (ABCC2) In Stock
Organism species: Mus musculus (Mouse)
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- Customized Service n/a Monoclonal Antibody to ATP Binding Cassette Transporter C2 (ABCC2) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to ATP Binding Cassette Transporter C2 (ABCC2) Polyclonal Antibody Customized Service Offer
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- Customized Service n/a ELISA Kit for ATP Binding Cassette Transporter C2 (ABCC2) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant ATP Binding Cassette Transporter C2 (ABCC2) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to ATP Binding Cassette Transporter C2 (ABCC2) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to ATP Binding Cassette Transporter C2 (ABCC2) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for ATP Binding Cassette Transporter C2 (ABCC2) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for ATP Binding Cassette Transporter C2 (ABCC2) ELISA Kit Customized Service Offer